Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

p230 trans Golgi Mouse anti-Human, Unlabeled, Clone: 15, BD

Mouse Monoclonal Antibody

Manufacturer:  BD Biosciences 611280

 View more versions of this product

Catalog No. BDB611280


Add to cart

Description

Description

The Golgi apparatus is a very complex and dynamic organelle that functions in protein sorting and modification. Numerous structural and regulatory proteins are involved in the budding, docking, and fusion of Golgi-directed vesicles. p230 trans Golgi is a peripheral membrane protein associated with the cytosolic face of the trans Golgi network (TGN). Protein sequence analysis indicates that it is highly hydrophilic and contains two proline-rich regions, as well as a high frequency of heptad repeats which are characteristic of α-helices that form dimeric coiled-coiled structures. Additionally, p230 trans Golgi contains a ESLALEELEL sequence, a motif of the acidic granin proteins that are found in secretory granules of neuroendocrine cells. p230 trans Golgi cycles between the cytosol and the TGN via non-clathrin coated vesicles in a G protein-dependent manner. The localization of p230 trans Golgi to the TGN is dependent on aromatic residues in its C-terminal non-coiled coil domain. Thus, p230 trans-Golgi is aTGN-specific protein that is important for the biogenesis of distinct populations of non-clathrin coated vesicles and, thus, functions in vesicular transport from the TGN.

Host Species: Mouse
Clone: 15
Isotype: IgG1
Species Reactivity: Human
Immunogen: Human p230 trans Golgi aa. 2063-2179
Formula Weight [Chemical]: 230kDa

Immunofluorescence, Western Blotting

Specifications

Specifications

p230 trans Golgi
15
Unconjugated
Affinity Purified
Human p230 trans Golgi aa. 2063-2179
50μg
Cell Biology
Primary
Human
Western Blot
250μg/mL
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Murine
IgG1
RUO
Store undiluted at -20°C.
Monoclonal
Documents
Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit

For Research Use Only.