MilliporeSigma™ anti-p38 MAP Kinase (341-360), Polyclonal

Rabbit Polyclonal Antibody

Supplier:  MilliporeSigma™ 506123200UL

Catalog No. 50-612-3200UL

Description

Specifically detects p38 MAP Kinase (341-360) Clone: in Human, Mouse, Rat samples, and it is validated for Flow Cytometry, Immunohistochemistry (Paraffin), Immuno Blotting

p38 MAP kinase (MAPK), also called RK and CSBP, is the mammalian homologue of the yeast HOG kinase and participates in a cascade controlling cellular responses to cytokines and stress. Like the SAPK/JNK pathway, p38 MAPK is activated by a variety of cellular stresses including osmotic shock, inflammatory cytokines, lipopolysaccharides (LPS), UV light and growth factors. Both MKK3 and SEK phosphorylate p38 on tyrosine and threonine at the sequence TGY resulting in p38 activation. Activated p38 MAPK has been shown to phosphorylate and activate MAPKAP kinase-2 and to phosphorylate the transcription factors ATF-2 and Max.

Specifications

• Antigen: p38 MAP Kinase (341-360)
• Classification: Polyclonal
• Formulation: In 150mM NaCl, 10mM HEPES, 50% glycerol, 0.01% BSA, pH 7.5.
• Immunogen: a synthetic peptide (TYDEYISFVPPPLDQEEMES) corresponding to amino acids 341-360 of human p38 MAP kinase
• Regulatory Status: RUO
• Test Specificity: Recognizes the ∽38kDa p38 MAPK protein. Antibody Target Gene Symbol: MAPK14 Target Synonym: CRK1, CSBP, CSBP1, CSBP2, CSPB1, EXIP, Hog, MAPK p38, MGC102436, MGC105413, MXI2, P38, P38 KINASE, P38 Map Kinase, p38 Mapk alpha, P38-ALPHA, p38-RK, p38/Hog1, p38/Mpk2, P38/RK, p38a, p38Hog, p38MAPK, PRKM14, PRKM15, RK, SAPK2A Entrez Gene Name: mitogen-activated protein kinase 14
• Content And Storage: −20°C
• Isotype: IgG

• Applications: Flow Cytometry, Immunoblot, Immunoblot, Immunohistochemistry (Paraffin)
• Conjugate: Unconjugated
• Host Species: Rabbit
• Quantity: 200 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Form: Purified

For Research Use Only