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Description
This gene encodes an acetylhydrolase that catalyzes the removal of an acetyl group from the glycerol backbone of platelet-activating factor. The encoded enzyme is a subunit of the platelet-activating factor acetylhydrolase isoform 1B complex, which consists of the catalytic beta and gamma subunits and the regulatory alpha subunit. This complex functions in brain development. A translocation between this gene on chromosome 19 and the CDC-like kinase 2 gene on chromosome 1 has been observed, and was associated with mental retardation, ataxia, and atrophy of the brain. Alternatively spliced transcript variants have been described. [provided by RefSeq
Specifications
Specifications
| Antigen | PAFAH1B3 |
| Applications | ELISA, Western Blot |
| Classification | Monoclonal |
| Clone | 3G6 |
| Conjugate | Unconjugated |
| Description | Mouse monoclonal antibody raised against a full-length recombinant PAFAH1B3. |
| Formulation | PBS with no preservative; pH 7.4 |
| Gene | PAFAH1B3 |
| Gene Accession No. | BC003016 |
| Gene Symbols | PAFAH1B3 |
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