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PAK6 Rabbit anti-Human, Polyclonal, Invitrogen™

Catalog No. PIPA528674
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PIPA528674 100 μL
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Catalog No. PIPA528674 Supplier Thermo Scientific Supplier No. PA528674

Rabbit Polyclonal Antibody

PA5-28674 targets PAK6 in IHC (P) and WB applications and shows reactivity with Human samples. The PA5-28674 immunogen is recombit fragment corresponding to a region within amino acids 307 and 681 of Human PAK6. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.

This gene encodes a member of the p21-activated kinase (PAK) family. The proteins of this family are Rac/Cdc42-associated Ste20-like Ser/Thr protein kinases, characterized by a highly conserved amino-terminal Cdc42/Rac interactive binding (CRIB) domain and a carboxyl-terminal kinase domain. PAK kinases are implicated in the regulation of a number of cellular processes, including cytoskeleton rearrangement, apoptosis and the MAP kinase signaling pathway. The protein encoded by this gene was found to interact with androgen receptor (AR), which is a steroid hormone-dependent transcription factor that is important for male sexual differentiation and development. This gene was found to be highly expressed in testis and prostate tissues and the encoded protein was shown to cotranslocate into the nucleus with AR in response to androgen. Alternatively spliced transcript variants encoding the same protein have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PAK6
Applications Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Gene PAK6
Gene Accession No. Q9NQU5
Gene Alias PAK5, PAK-5, PAK-6, p21(CDKN1A)-activated kinase 6, p21-activated kinase 6, p21-activated protein kinase 6, serine/threonine-protein kinase PAK 6
Gene Symbols PAK6
Host Species Rabbit
Immunogen Recombit fragment corresponding to a region within amino acids 307 and 681 of Human PAK6
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 56924
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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