alpha Synuclein Rabbit anti-Human, Rat, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA118253
Synuclein family of proteins is abundantly expressed in neuronal cytosol and presynaptic terminals. In vertebrates they are encoded by three different genes. Synucleins have been specifically implemented in three major diseases: Alzheimer's (AD), Parkinson's PD) and breast cancer. In AD, a peptide derived from alpha synuclein forms an intrinsic component of plaque amyloid. In PD, an alpha synuclein accumulates in Lewy bodies. An allele of alpha synuclein has been linked to many familial cases of PD. In breast cancer increased expression of gamma synuclein correlates with the disease progression. Synucleins appear to be involved in the membrane plasticity in developing song control system of songbirds.PA1-18253 detects alpha, beta, and gamma Synuclein from human and rat samples.PA1-18253 has been successfully used in immunohistochemistry and Western blot procedures.The PA1-18253 immunogen is a synthetic peptide corresponding to residues A K E G V V A A A E K T K Q G V of a consensus part of human alpha-, beta-, and gamma synuclein proteins, conjugated to diphteria toxoid.Reconstitute with 100 ul of distilled water.
|whole serum with no preservative|
|MGC110988, NACP, PARK1, PARK4, PD1|
|Immunohistochemistry, Western Blot|
|Synthetic peptide corresponding to residues A K E G V V A A A E K T K Q G V of a consensus part of human alpha-, beta-, and gamma synuclein proteins.|
|-20° C, Avoid Freeze/Thaw Cycles|
We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.
Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.Ok