poly(A)-specific ribonuclease (deadenylation nuclease), Mouse, Polyclonal Antibody, Abnova
Mouse polyclonal antibody raised against a partial recombinant PARN.
Manufacturer: Abnova Corporation H00005073A01
The protein encoded by this gene is a 3'-exoribonuclease, with similarity to the RNase D family of 3'-exonucleases. It prefers poly(A) as the substrate, hence, efficiently degrades poly(A) tails of mRNAs. Exonucleolytic degradation of the poly(A) tail is often the first step in the decay of eukaryotic mRNAs. This protein is also involved in silencing of certain maternal mRNAs during oocyte maturation and early embryonic development, as well as in nonsense-mediated decay (NMD) of mRNAs that contain premature stop codons. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeqSequence: AESYRIQTYAEYMGRKQEEKQIKRKWTEDSWKEADSKRLNPQCIPYTLQNHYYRNNSFTAPSTVGKRNLSPSQEEAGLEDGVSGEISDTELEQTDSCAE
|poly(A)-specific ribonuclease (deadenylation nuclease)|
|Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|ELISA, Western Blot|
|Mouse polyclonal antibody raised against a partial recombinant PARN.|
|PARN (NP_002573, 501 a.a. ~ 599 a.a) partial recombinant protein with GST tag.|
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