Invitrogen™ PASK Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA521879

Catalog No. PIPA521879

Description

Recommended positive controls: 293T, H1299, HepG2, Molt-4, Raji. Predicted reactivity: Mouse (83%), Rat (82%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

PASK is an evolutionarily conserved protein present in yeast, flies, and mammals. PAS domains regulate the function of many intracellular signaling pathways in response to both extrinsic and intrinsic stimuli. It is a conserved gene product found in yeast as well as mammals. PASKIN contains two domains (PAS A and PAS B) as well as a serine/threonine kinase domain related to AMP kinases. PASKIN activity leads to decreased carbohydrate storage, as well as increased protein synthesis. PASKIN-dependent phosphorylation inhibits the activity of mammalian glycogen synthase.

Specifications

• Antigen: PASK
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PASK
• Gene Alias: Kiaa0135; mKIAA0135; OTTMUSP00000024404; PAS domain containing serine/threonine kinase; PAS domain-containing serine/threonine-protein kinase; PASK; PASKIN; PAS-kinase; per-arnt-sim (PAS) domain kinase; STK37
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 23178
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.87 mg/mL
• Formulation: 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q96RG2
• Gene Symbols: PASK
• Immunogen: Recombinant protein encompassing a sequence within the C-terminus region of human PASK. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov