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PCDHGC3 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA523650

Catalog No. PIPA523650

This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.


Description

Description

This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.
Specifications

Specifications

PCDHGC3
Polyclonal
PBS with 0.09% sodium azide
Q9UN70
PC43, PCDH-GAMMA-C3, PCDH2, cadherin-like 2, protocadherin 2, protocadherin 43, protocadherin gamma-C3, protocadherin-2, protocadherin-43
Rabbit
IgG
400 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
5098
Flow Cytometry, Immunohistochemistry, Western Blot
Unconjugated
PCDHGC3
Liquid
PCDHGC3
KLH conjugated synthetic peptide between 511-539 amino acids from the central region of human PCDHGC3
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Documents
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