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phosphoenolpyruvate carboxykinase 1 (soluble), Mouse, Clone: 3E4, Abnova™

Catalog No. 89014164 Shop All Abnova Corporation Products
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89-014-164 100 μg
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Catalog No. 89-014-164 Supplier Abnova Corporation Supplier No. H00005105M01
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Description

Mouse monoclonal antibody raised against a full-length recombinant PCK1.

This gene is a main control point for the regulation of gluconeogenesis. The cytosolic enzyme encoded by this gene, along with GTP, catalyzes the formation of phosphoenolpyruvate from oxaloacetate, with the release of carbon dioxide and GDP. The expression of this gene can be regulated by insulin, glucocorticoids, glucagon, cAMP, and diet. Defects in this gene are a cause of cytosolic phosphoenolpyruvate carboxykinase deficiency. A mitochondrial isozyme of the encoded protein also has been characterized. [provided by RefSeq

Sequence: MPPQLQNGLNLSAKVVQGSLDSLPQAVREFLENNAELCQPDHIHICDGSEEENGRLLGQMEEEGILRRLKKYDNCWLALTDPRDVARIESKTVIVTQEQRDTVPIPKTGLSQLGRWMSEEDFEKAFNARFPGCMKGRTMYVIPFSMGPLGSPLSKIGIELTDSPYVVASMRIMTRMGTPVLEALGDGEFVKCLHSVGCPLPLQKPLVNNWPCNPELTLIAHLPDRREIISFGSGYGGNSLLGKKCFALRMASRLAKEEGWLAEHMLVLGITNPEGEKKYLAAAFPSACGKTNLAMMNPSLPGWKVECVGDDIAWMKFDAQGHLRAINPENGFFGVAPGTSVKTNPNAIKTIQKNTIFTNVAETSDGGVYWEGIDEPLASGVTITSWKNKEWSSEDGEPCAHPNSRFCTPASQCPIIDAAWESPEGVPIEGIIFGGRRPAGVPLVYEALSWQHGVFVGAAMRSEATAAAEHKGKIIMHDPFAMRPFFGYNFGKYLAHWLSMAQHPAAKLPKIFHVNWFRKDKEGKFLWPGFGENSRVLEWMFNRIDGKASTKLTPIGYIPKEDALNLKGLGHINMMELFSISKEFWEKEVEDIEKYLEDQVNADLPCEIEREILALKQRISQM

Specifications

Antigen phosphoenolpyruvate carboxykinase 1 (soluble)
Applications ELISA, Immunofluorescence, Immunoprecipitation, Western Blot
Classification Monoclonal
Clone 3E4
Conjugate Unconjugated
Description Mouse monoclonal antibody raised against a full length recombinant PCK1.
Formulation PBS with no preservative; pH 7.4
Gene PCK1
Gene Accession No. BC023978
Gene Alias MGC22652/PEPCK-C/PEPCK1/PEPCKC
Gene Symbols PCK1
Host Species Mouse
Immunogen PCK1 (AAH23978, 1 a.a. ∼ 622 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification Method Affinity Purified
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5105
Target Species Human
Content And Storage Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Product Type Antibody
Isotype IgG1 κ
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