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PCNA Mouse anti-Human, Unlabeled, Clone: PC10, BD

Catalog No. BDB555566 Shop All BD Biosciences Products
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BDB555566 0.1 mg
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Catalog No. BDB555566 Supplier BD Biosciences Supplier No. 555566

Description

Mouse Monoclonal Antibody

The Proliferating Cell Nuclear Antigen (PCNA) was initially identified as a nuclear antigen in proliferating cells and was subsequently described as a subunit for DNA polymerase δ. PCNA protein levels peak during the S-phase of the cell cycle, at which time it forms a complex with the p21 inhibitor. PCNA is almost undetectable in other phases of the cycle. Because of its unique expression, PCNA has been extensively used in studies associating the prognosis of tumor progression and neoplastic proliferation. Human PCNA has been reported to be 262 amino acids with an apparent molecular weight of 36kDa. This antibody is routinely tested by flow cytometric analysis, immunohistochemistry and immunofluorescent imaging. Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.

Immunohistochemistry, Immunohistochemistry (Frozen), Intracellular Staining

TRUSTED_SUSTAINABILITY

Specifications

Antigen PCNA
Applications Flow Cytometry
Classification Monoclonal
Clone PC10
Concentration 0.5mg/mL
Conjugate Unconjugated
Formulation Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species Mouse
Immunogen Not reported
Purification Method Affinity Purified
Quantity 0.1 mg
Regulatory Status RUO
Research Discipline Cell Biology
Primary or Secondary Primary
Target Species Human
Content And Storage Store undiluted at 4°C
Isotype IgG2a κ
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For Research Use Only.

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