anti-PDCD6IP Ab-1, Polyclonal, Abnova
Manufacturer: Abnova Corporation H00010015B01
This gene encodes a protein thought to participate in programmed cell death. Studies using mouse cells have shown that overexpression of this protein can block apoptosis. In addition, the product of this gene binds to the product of the PDCD6 gene, a protein required for apoptosis, in a calcium-dependent manner. This gene product also binds to endophilins, proteins that regulate membrane shape during endocytosis. Overexpression of this gene product and endophilins results in cytoplasmic vacuolization which may be partly responsible for the protection against cell death.
Detection Antibody, Immunofluorescence, Western Blotting
|programmed cell death 6 interacting protein|
|PDCD6IP (AAH20066, 1 a.a. ∽868 a.a) full-length human protein.|
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