PFKFB2, Rabbit, Monoclonal Antibody, Abnova™

Rabbit monoclonal antibody raised against a human PFKFB2 peptide using ARM Technology.

Supplier:  Abnova Corporation H00005208K

Catalog No. 89-202-775

Includes: Up to three rabbit IgG clones of 1mg each will be delivered to customer.

Description

The protein encoded by this gene is involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls glycolysis in eukaryotes. The encoded protein has a 6-phosphofructo-2-kinase activity that catalyzes the synthesis of fructose-2,6-bisphosphate, and a fructose-2,6-biphosphatase activity that catalyzes the degradation of fructose-2,6-bisphosphate. This protein regulates fructose-2,6-bisphosphate levels in the heart, while a related enzyme encoded by a different gene regulates fructose-2,6-bisphosphate levels in the liver and muscle. This enzyme functions as a homodimer. Two transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq

Library Construction: Nonfusion antibody library from rabbit spleen (ARM Technology)
Expression: Overexpression vector and transfection into 293H cell line

Order Info

1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.

Specifications

• Antigen: PFKFB2
• Classification: Monoclonal
• Conjugate: Unconjugated
• Formulation: In 1X PBS, pH 7.4
• Gene Accession No.: PFKFB2
• Gene Symbols: PFKFB2
• Immunogen: A synthetic peptide of human PFKFB2
• Regulatory Status: RUO
• Gene ID (Entrez): 5208
• Content And Storage: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
• Isotype: IgG

• Applications: ELISA, Western Blot
• Concentration: 1mg
• Description: 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
• Gene: PFKFB2
• Gene Alias: DKFZp781D2217, MGC138308, MGC138310, PFK-2/FBPase-2
• Host Species: Rabbit
• Quantity: 1 mg x up to 3 Abs
• Primary or Secondary: Primary
• Target Species: Human
• Form: Liquid