Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

MilliporeSigma™ anti-PGC-1alpha, Polyclonal

Rabbit Polyclonal Antibody

Manufacturer:  MilliporeSigma™ ST1204100UL

Catalog No. ST1204100UL


Add to cart

Description

Description

Specifically detects PGC-1α Clone: in Human, Mouse, Rat samples, and it is validated for Immunoprecipitation

PGC-1α is a co-activator of PPARα, PPARγ, and other transcription factors that regulate the transcriptonal program of adaptive thermogenesis in brown adipose tissue, hepatic/renal gluconeogenesis, and muscle fiber type switching. The full length protein is detected at 113kDa and is induced in BAT by cold exposure, in liver and kidney by fasting, and in skeletal muscle by exercise. Alternative splicing of the full length gene produces a 270 aa N-terminal splice variant that migrates at~38kDa and is induced by the same physiological signals which induce expression of the full length protein. The N-terminal PGC-1α splice variant is also subject to post translational modifications which alter its migration and apparent molecular weight.
Specifications

Specifications

PGC-1α
Unconjugated
Purified
A recombinant protein consisting of amino acids 1-120 of mouse PGC-1α
100μL
≤ -70°C
Polyclonal
Human, Murine, Rat
Immunoprecipitation
In 50mM PBS
Rabbit
IgG
RUO
Primary
Recognizes the ∽113kDa PGC-1α protein in BAT cells.
Documents
Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit

For Research Use Only