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Phospho-ACK1 (Tyr518) Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA513016

Catalog No. PIPA513016


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Description

Description

This antibody is predicted to react with bovine based on sequence homology.

ACK1 is a tyrosine kinase that binds Cdc42Hs in its GTP-bound form and inhibits both the intrinsic and GTPase-activating protein (GAP)-stimulated GTPase activity of Cdc42Hs. This binding is mediated by a unique sequence of 47 amino acids C-terminal to an SH3 domain. The protein may be involved in a regulatory mechanism that sustains the GTP-bound active form of Cdc42Hs and which is directly linked to a tyrosine phosphorylation signal transduction pathway.
Specifications

Specifications

Phospho-ACK1 (Tyr518)
Polyclonal
Unconjugated
TNK2
Liquid
TNK2
KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y518 of human ACK1
Antigen Affinity Chromatography, Protein A
RUO
Antibody
Polyclonal
Human
Dot Blot
0.3 mg/mL
PBS with 0.09% sodium azide
Q07912
Activated p21cdc42Hs kinase
Rabbit
IgG
400 μL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
10188
Documents
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