Phospho-Cdc25A (Ser75) Rabbit anti-Human, Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA512563

Catalog No. PIPA512563

Description

CDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated. Two transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: Phospho-Cdc25A (Ser75)
• Classification: Polyclonal
• Formulation: PBS with 0.09% sodium azide
• Gene Accession No.: P30304, P48964
• Gene Alias: M-phase inducer phosphatase 1; Dual specificity phosphatase Cdc25A; CDC25A;
• Host Species: Rabbit
• Isotype: IgG
• Quantity: 400 μL
• Storage Requirements: -20° C, Avoid Freeze/Thaw Cycles
• Primary or Secondary: Primary
• Gene ID (Entrez): 12530, 993

• Applications: Immunohistochemistry, Western Blot
• Conjugate: Unconjugated
• Gene: CDC25A
• Format: Liquid
• Gene Symbols: CDC25A
• Immunogen: KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S75 of human CDC25A
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Type: Antibody
• Monoclonal or Polyclonal: Polyclonal
• Target Species: Human, Mouse