MilliporeSigma™ anti-phospho TDP-43 (Ser409/Ser410), Clone: 1D3, ™

Supplier:  MilliporeSigma™ MABN14/DEL

Catalog No. 50-175-917

Description

TAR DNA-binding protein 43 (TDP-43) belongs to the hnRNP protein family and plays an important role in transcription, pre-mRNA splicing, mRNA stability and mRNA transport. It is involved in splicing of the apolipoprotein A-II and cystic fibrosis transmembrane gene. This protein is highly expressed in the pancreas, placenta, lung, genital tract and spleen. Mutations in TDP-43 have been associated with amyotrophic lateral sclerosis, frontotemporal dementia, Parkinson's disease and Alzheimer's disease.

Host Species: Rat
Clone: 1D3
Isotype: IgG2a, κ
Cross Reactivity: Human
Immunogen: Ovalbumin-conjugated linear peptide corresponding to human TDP-43 phosphorylated at Ser409/Ser410.

ELISA, Immunohistochemistry, Western Blotting

Specifications

• Antigen: phospho TDP-43 (Ser409/Ser410)
• Clone: 1D3
• Host Species: Rat
• Quantity: 100 μg
• Target Species: Human
• Isotype: IgG2a κ

• Classification: Monoclonal
• Conjugate: Unconjugated
• Immunogen: Ovalbumin-conjugated linear peptide corresponding to human TDP-43 phosphorylated at Ser409/Ser410.
• Primary or Secondary: Primary
• Form: Purified