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MilliporeSigma™ anti-PhosphoDetect Fos (pSer374) Clone: 340000,

Catalog No. ST10291SET Shop All MilliporeSigma Products
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1 Set
Conjugate:
Unconjugated
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Catalog No. Quantity Conjugate
ST10291SET 1 Set Unconjugated
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Catalog No. ST10291SET Supplier MilliporeSigma™ Supplier No. ST10291SET
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Description

Mouse Monoclonal Antibody

Specifically detects Fos (pSer374) Clone: 340000 in Human samples, and it is validated for ELISA, Immuno Blotting

The early gene product c-Fos is expressed following mitogenic stimulation and functions as a sensor for MAPK signal duration. When MAPK activation is transient, MAPK activity declines before accumulation of the c-Fos protein. When MAPK activation is sustained, c-Fos is phosphorylated by MAPK at Ser374. Phosphorylation stabilizes the Fos protein and primes c-Fos for additional phosphorylation at Thr325.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Fos (pSer374)
Applications ELISA, Immunoblot, Immunoblot
Classification Monoclonal
Clone 340000
Conjugate Unconjugated
Formulation 100μg antibody lyophilized from 2X PBS, PEG, sucrose and 200μL lyophilized control lysate from EGF-treated HEPG2 cells.
Host Species Mouse
Immunogen a synthetic phosphopeptide corresponding to amino acids surrounding the Ser374 phosphorylation site of human c-Fos
Quantity 1 Set
Regulatory Status RUO
Primary or Secondary Primary
Test Specificity Recognizes the ∽55kDa c-Fos protein phosphorylated at Ser374. Does not detect the unphosphorylated form.
Target Species Human
Content And Storage −20°C
Form Purified
Isotype IgG1
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For Research Use Only

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