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MilliporeSigma™ anti-PhosphoDetect VASP (pSer157) Clone: 5C6,

Catalog No. 676604100UG Shop All MilliporeSigma Products
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Quantity:
100 μg
Conjugate:
Unconjugated
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Catalog No. Quantity Conjugate
67-660-4100UG 100 μg Unconjugated
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Catalog No. 67-660-4100UG Supplier MilliporeSigma™ Supplier No. 676604100UG
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Description

Mouse Monoclonal Antibody

Specifically detects VASP (pSer157) Clone: 5C6 in Human, Mouse samples, and it is validated for ELISA, Immunocytochemistry, Immunoprecipitation, Immuno Blotting

VASP (vasodilator-stimulated phosphoprotein), an established substrate of cAMP- and cGMP-dependent protein kinases in vitro and in living cells, is associated with focal adhesions, microfilaments, and membrane regions of high dynamic activity. VASP binds in vitro to profilin, zyxin, vinculin, and the Listeria sp. surface protein ActA. VASP also promotes actin nucleation and binds to actin filaments in vitro and associates with stress fibers in cells. Studies imply that VASP phosphorylation may act as an immediate negative regulator of actin dynamics. Phosphorylation of Ser157 in VASP can be used as a measure of PKA activity.
TRUSTED_SUSTAINABILITY

Specifications

Antigen VASP (pSer157)
Applications ELISA, Immunoblot, Immunoblot, Immunocytochemistry, Immunoprecipitation
Classification Monoclonal
Clone 5C6
Conjugate Unconjugated
Formulation Lyophilized from PBS, PEG, sucrose.
Host Species Mouse
Immunogen a synthetic phosphopeptide corresponding to amino acids surrounding the Ser157 phosphorylation site of human VASP
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Test Specificity Recognizes the the ∽50kDa VASP protein phosphorylated at Ser157.
Target Species Human, Mouse
Content And Storage −20°C
Form Purified
Isotype IgG1
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For Research Use Only

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