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Description
This gene encodes a member of the mammalian PIAS [protein inhibitor of activated STAT-1 (signal transducer and activator of transcription-1)] family. This member contains a putative zinc-binding motif and a highly acidic region. It inhibits STAT1-mediated gene activation and the DNA binding activity, binds to Gu protein/RNA helicase II/DEAD box polypeptide 21, and interacts with androgen receptor (AR). It functions in testis as a nuclear receptor transcriptional coregulator and may have a role in AR initiation and maintenance of spermatogenesis. [provided by RefSeq
Specifications
Specifications
| Antigen | PIAS1 |
| Applications | Western Blot |
| Classification | Polyclonal |
| Conjugate | Unconjugated |
| Description | Mouse polyclonal antibody raised against a full-length human PIAS1 protein. |
| Formulation | No additive |
| Gene | PIAS1 |
| Gene Accession No. | NM_016166.1 |
| Gene Alias | DDXBP1/GBP/GU/RH-II/MGC141878/MGC141879/ZMIZ3 |
| Gene Symbols | PIAS1 |
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