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paired-like homeodomain 2, Mouse, Clone: 3D2, Abnova™
Mouse monoclonal antibody raised against a full-length recombinant PITX2.
Supplier: Abnova Corporation H00005308M02
Description
This gene encodes a member of the RIEG/PITX homeobox family, which is in the bicoid class of homeodomain proteins. The encoded protein acts as a transcription factor and regulates procollagen lysyl hydroxylase gene expression. This protein plays a role in the terminal differentiation of somatotroph and lactotroph cell phenotypes, is involved in the development of the eye, tooth and abdominal organs, and acts as a transcriptional regulator involved in basal and hormone-regulated activity of prolactin. Mutations in this gene are associated with Axenfeld-Rieger syndrome, iridogoniodysgenesis syndrome, and sporadic cases of Peters anomaly. A similar protein in other vertebrates is involved in the determination of left-right asymmetry during development. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq
Sequence: MNCMKGPLHLEHRAAGTKLSAVSSSSCHHPQPLAMASVLAPGQPRSLDSSKHRLEVHTISDTSSPEAAEKDKSQQGKNEDVGAEDPSKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQAELCKNGFGPQFNGLMQPYDDMYPGYSYNNWAAKGLTSASLSTKSFPFFNSMNVNPLSSQSMFSPPNSISSMSMSSSMVPSAVTGVPGSSLNSLNNLNNLSSPSLNSAVPTPACPYAPPTPPYVYRDTCNSSLASLRLKAKQHSSFGYASVQNPASNLSACQYAVDRPVSpecifications
paired-like homeodomain 2 | |
Monoclonal | |
Unconjugated | |
PBS with no preservative; pH 7.4 | |
BC013998 | |
PITX2 | |
PITX2 (AAH13998, 1 a.a. ∼ 324 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. | |
100 μg | |
Stem Cell Biology | |
Primary | |
Human | |
Antibody |
ELISA, Western Blot | |
3D2 | |
Mouse monoclonal antibody raised against a full length recombinant PITX2. | |
PITX2 | |
ARP1/Brx1/IDG2/IGDS/IGDS2/IHG2/IRID2/MGC111022/MGC20144/Otlx2/PTX2/RGS/RIEG/RIEG1/RS | |
Mouse | |
Affinity Purified | |
RUO | |
Yes | |
5308 | |
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. | |
IgG1 κ |
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