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paired-like homeodomain 2, Mouse, Clone: 3D2, Abnova™

Mouse monoclonal antibody raised against a full-length recombinant PITX2.

Supplier:  Abnova Corporation H00005308M02

Catalog No. 89-000-883


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Description

Description

This gene encodes a member of the RIEG/PITX homeobox family, which is in the bicoid class of homeodomain proteins. The encoded protein acts as a transcription factor and regulates procollagen lysyl hydroxylase gene expression. This protein plays a role in the terminal differentiation of somatotroph and lactotroph cell phenotypes, is involved in the development of the eye, tooth and abdominal organs, and acts as a transcriptional regulator involved in basal and hormone-regulated activity of prolactin. Mutations in this gene are associated with Axenfeld-Rieger syndrome, iridogoniodysgenesis syndrome, and sporadic cases of Peters anomaly. A similar protein in other vertebrates is involved in the determination of left-right asymmetry during development. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq

Sequence: MNCMKGPLHLEHRAAGTKLSAVSSSSCHHPQPLAMASVLAPGQPRSLDSSKHRLEVHTISDTSSPEAAEKDKSQQGKNEDVGAEDPSKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQAELCKNGFGPQFNGLMQPYDDMYPGYSYNNWAAKGLTSASLSTKSFPFFNSMNVNPLSSQSMFSPPNSISSMSMSSSMVPSAVTGVPGSSLNSLNNLNNLSSPSLNSAVPTPACPYAPPTPPYVYRDTCNSSLASLRLKAKQHSSFGYASVQNPASNLSACQYAVDRPV
Specifications

Specifications

paired-like homeodomain 2
Monoclonal
Unconjugated
PBS with no preservative; pH 7.4
BC013998
PITX2
PITX2 (AAH13998, 1 a.a. ∼ 324 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
100 μg
Stem Cell Biology
Primary
Human
Antibody
ELISA, Western Blot
3D2
Mouse monoclonal antibody raised against a full length recombinant PITX2.
PITX2
ARP1/Brx1/IDG2/IGDS/IGDS2/IHG2/IRID2/MGC111022/MGC20144/Otlx2/PTX2/RGS/RIEG/RIEG1/RS
Mouse
Affinity Purified
RUO
Yes
5308
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
IgG1 κ
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