PKM2, Rabbit, Monoclonal Antibody, Abnova™

Rabbit monoclonal antibody raised against a human PKM2 peptide using ARM Technology.

Supplier:  Abnova Corporation H00005315K

Catalog No. 89-202-768

Includes: Up to three rabbit IgG clones of 1mg each will be delivered to customer.

Description

This gene encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and pyruvate. This protein has been shown to interact with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis. Three alternatively spliced transcript variants encoding two distinct isoforms have been reported. [provided by RefSeq

Library Construction: Nonfusion antibody library from rabbit spleen (ARM Technology)
Expression: Overexpression vector and transfection into 293H cell line

Order Info

1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.

Specifications

• Antigen: PKM2
• Classification: Monoclonal
• Conjugate: Unconjugated
• Formulation: In 1X PBS, pH 7.4
• Gene Accession No.: PKM2
• Gene Symbols: PKM2
• Immunogen: A synthetic peptide of human PKM2
• Regulatory Status: RUO
• Gene ID (Entrez): 5315
• Content And Storage: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
• Isotype: IgG

• Applications: ELISA, Western Blot
• Concentration: 1mg
• Description: pyruvate kinase, muscle
• Gene: PKM2
• Gene Alias: CTHBP, MGC3932, OIP3, PK3, PKM, TCB, THBP1
• Host Species: Rabbit
• Quantity: 1 mg x up to 3 Abs
• Primary or Secondary: Primary
• Target Species: Human
• Form: Liquid