PMS2, Rabbit, Monoclonal Antibody, Abnova™

Rabbit monoclonal antibody raised against a human PMS2 peptide using ARM Technology.

Supplier:  Abnova Corporation H00005395K

Catalog No. 89-202-829

Includes: Up to three rabbit IgG clones of 1mg each will be delivered to customer.

Description

This gene is one of the PMS2 gene family members found in clusters on chromosome 7. The product of this gene is involved in DNA mismatch repair. It forms a heterodimer with MLH1 and this complex interacts with other complexes bound to mismatched bases. Mutations in this gene are associated with hereditary nonpolyposis colorectal cancer, Turcot syndrome, and are a cause of supratentorial primitive neuroectodermal tumors. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq

Library Construction: Nonfusion antibody library from rabbit spleen (ARM Technology)
Expression: Overexpression vector and transfection into 293H cell line

Order Info

1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.

Specifications

• Antigen: PMS2
• Classification: Monoclonal
• Conjugate: Unconjugated
• Formulation: In 1X PBS, pH 7.4
• Gene Accession No.: PMS2
• Gene Symbols: PMS2
• Immunogen: A synthetic peptide of human PMS2
• Regulatory Status: RUO
• Gene ID (Entrez): 5395
• Content And Storage: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
• Isotype: IgG

• Applications: ELISA, Western Blot
• Concentration: 1mg
• Description: PMS2 postmeiotic segregation increased 2 (S. cerevisiae)
• Gene: PMS2
• Gene Alias: HNPCC4, PMS2CL, PMSL2
• Host Species: Rabbit
• Quantity: 1 mg x up to 3 Abs
• Primary or Secondary: Primary
• Target Species: Human
• Form: Liquid