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MilliporeSigma™ anti-Porin (Ab-5) (185-197), Polyclonal

Catalog No. PC54850UG Shop All MilliporeSigma Products
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Quantity:
50 μg
Conjugate:
Unconjugated
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Catalog No. Quantity Conjugate
PC54850UG 50 μg Unconjugated
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Catalog No. PC54850UG Supplier MilliporeSigma™ Supplier No. PC54850UG
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Description

Rabbit Polyclonal Antibody

Specifically detects Porin (Ab-5) (185-197) Clone: in Human, Rat samples, and it is validated for Immuno Blotting

The Voltage-Dependent Anion Channel (VDAC or mitochondrial Porin) is a constituent of the outer mitochondrial membrane. The VDAC protein is thought to form the major pores through which adenine nucleotides are transferred through the outer mitochondrial membrane. VDAC has also been implicated in the formation of the mitochondrial permeability transition pore complex in apoptotic cells. This complex, formed by VDAC, adenine nucleotide translocator (ANT), and cyclophilin D (CypD), is thought to allow the mitochondria to undergo metabolic uncoupling and irreversible morphologic changes that ultimately destroy the mitochondria during apoptosis. There are also strong indications that the VDAC-adenine nucleotide translocase-CyP-D complex can recruit a number of other proteins, including Bax, and that the complex is utilized in some capacity during apoptosis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Porin (Ab-5) (185-197)
Applications Immunoblot
Classification Polyclonal
Conjugate Unconjugated
Formulation In PBS, 1mg/mL BSA.
Host Species Rabbit
Immunogen a synthetic peptide corresponding to amino acids 185-197 of human porin
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Test Specificity Recognizes the ∽31kDa porin protein.
Target Species Human, Rat
Content And Storage −20°C
Form Purified
Isotype IgG
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For Research Use Only

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