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Description
POU3F2 belongs to a large family of transcription factors that bind to the octameric DNA sequence ATGCAAAT. Most of these proteins share a highly homologous region, referred to as the POU domain, that occurs in several mammalian transcription factors, including the octamer-binding proteins Oct1 (POU2F1; MIM 164175) and Oct2 (POU2F2; MIM 164176) and the pituitary protein Pit1 (PIT1; MIM 173110). Class III POU genes are expressed predominantly in the central nervous system (CNS). It is likely that CNS-specific transcription factors such as these play an important role in mammalian neurogenesis by regulating their diverse patterns of gene expression (Schreiber et al., 1993 [PubMed 8441633]; Atanasoski et al., 1995 [PubMed 7601453]).[supplied by OMIM
Specifications
Specifications
| Antigen | POU3F2 |
| Applications | ELISA, Western Blot |
| Classification | Monoclonal |
| Clone | 1H5 |
| Conjugate | Unconjugated |
| Description | Mouse monoclonal antibody raised against a partial recombinant POU3F2. |
| Formulation | PBS with no preservative; pH 7.4 |
| Gene | POU3F2 |
| Gene Accession No. | NM_005604 |
| Gene Alias | BRN2/OCT7/OTF7/POUF3 |
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