PPARGC1A, Mouse, Clone: 2G8, Abnova™

Catalog No.	Quantity
89-002-783	100 μg

Catalog No. 89-002-783 Supplier Abnova Corporation Supplier No. H00010891M17

Description

Mouse monoclonal antibody raised against a partial recombinant PPARGC1A.

The protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPARgamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, and regulate the activities of, cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination. This protein may be also involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, and the development of obesity. [provided by RefSeq

Sequence: TRTELRDRFEVFGEIEECTVNLRDDGDSYGFITYRYTCDAFAALENGYTLRRSNETDFELYFCGRKQFFKSNYADLDSNSDDFDPASTKSKYDSLDFDSLLKEAQRSLRR

Specifications

• Antigen: PPARGC1A,
• Applications: ELISA, Western Blot
• Classification: Monoclonal
• Clone: 2G8
• Conjugate: Unconjugated
• Description: Mouse monoclonal antibody raised against a partial recombinant PPARGC1A.
• Formulation: In 1X PBS, pH 7.4
• Gene: PPARGC1A
• Gene Accession No.: NM_013261
• Gene Alias: LEM6/PGC-1(alpha)/PGC-1v/PGC1/PGC1A/PPARGC1
• Gene Symbols: PPARGC1A
• Host Species: Mouse
• Immunogen: PPARGC1A (NP_037393, 689 a.a. ∼ 798 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 10891
• Target Species: Human
• Content And Storage: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
• Form: Liquid
• Isotype: IgG2a κ