proteasome (prosome, macropain) subunit, beta type, 6, Mouse, Clone: S51, Abnova™

Catalog No.	Quantity
89-000-912	100 μg

Catalog No. 89-000-912 Supplier Abnova Corporation Supplier No. H00005694M02

Description

Mouse monoclonal antibody raised against a full-length recombinant PSMB6.

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 nonidentical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a nonlysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit in the proteasome. This catalytic subunit is not present in the immunoproteasome and is replaced by catalytic subunit 1i (proteasome beta 9 subunit). [provided by RefSeq

Sequence: MAATLLAARGAGPAPAWGPEAFTPDWESREVSTGTTIMAVQFDGGVVLGADSRTTTGSYIANRVTDELTPIHDRIFCCRSGSAADTQAVADAVTYQLGFHSIELNEPPLVHTAASLFKEMCYRYREDLMAGIIIAGWDPQEGGQVYSVPMGGMMVRQSFAIGGSGSSYIYGYVDATYREGMTKEECLQFTANALALAMERDGSSGGVIRLAAIAESGVERQVLLGDQIPKFAVATLPPA

Specifications

• Antigen: proteasome (prosome, macropain) subunit, beta type, 6
• Applications: ELISA, Immunofluorescence, Immunohistochemistry (PFA fixed), Western Blot
• Classification: Monoclonal
• Clone: S51
• Conjugate: Unconjugated
• Description: Mouse monoclonal antibody raised against a full length recombinant PSMB6.
• Formulation: PBS with no preservative; pH 7.4
• Gene: PSMB6
• Gene Accession No.: BC000835
• Gene Alias: DELTA/LMPY/MGC5169/Y
• Gene Symbols: PSMB6
• Host Species: Mouse
• Immunogen: PSMB6 (AAH00835, 1 a.a. ∼ 239 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
• Purification Method: Affinity Purified
• Quantity: 100 μg
• Regulatory Status: RUO
• Research Discipline: Stem Cell Biology
• Whole Molecule: Yes
• Primary or Secondary: Primary
• Gene ID (Entrez): 5694
• Target Species: Human
• Content And Storage: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
• Product Type: Antibody
• Isotype: IgG2b κ