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proteasome (prosome, macropain) 26S subunit, non-ATPase, 5, Rabbit, Purified MaxPab™ Polyclonal Antibody, Abnova™
Rabbit polyclonal antibody raised against a full-length human PSMD5 protein.
Supplier: Abnova Corporation H00005711D01P
Description
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 nonidentical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a nonlysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator base. [provided by RefSeq
Sequence: MAAQALALLREVARLEAPLEELRALHSVLQAVPLNELRQQAAELRLGPLFSLLNENHREKTTLCVSILERLLQAMEPVHVARNLRVDLQRGLIHPDDSVKILTLSQIGRIVENSDAVTEILNNAELLKQIVYCIGGENLSVAKAAIKSLSRISLTQAGLEALFESNLLDDLKSVMKTNDIVRYRVYELIIEISSVSPESLNYCTTSGLVTQLLRELTGEDVLVRATCIEMVTSLAYTHHGRQYLAQEGVIDQISNIIVGADSDPFSSFYLPGFVKFFGNLAVMDSPQQICERYPIFVEKVFEMIESQDPTMIGVAVDTVGILGSNVEGKQVLQKTGTRFERLLMRIGHQSKNAPVELKIRCLDAISSLLYLPPEQQTDDLLRMTESWFSSLSRDPLELFRGISSQPFPELHCAALKVFTAIANQPWAQKLMFNSPGFVEYVVDRSVEHDKASKDAKYELVKALANSKTIAEIFGNPNYLRLRTYLSEGPYYVKPVSTTAVEGAESpecifications
proteasome (prosome, macropain) 26S subunit, non-ATPase, 5 | |
Polyclonal | |
Rabbit polyclonal antibody raised against a full-length human PSMD5 protein. | |
PSMD5 | |
KIAA0072/MGC23145/S5B | |
Rabbit | |
Affinity Purified | |
RUO | |
5711 | |
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. | |
IgG |
Western Blot | |
Unconjugated | |
PBS with no preservative; pH 7.4 | |
NM_005047.2 | |
PSMD5 | |
PSMD5 (NP_005038.1, 1 a.a. ∼ 504 a.a) full-length human protein. | |
100 μg | |
Primary | |
Human, Mouse | |
Antibody |
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