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PTBP1, Rabbit, Monoclonal Antibody, Abnova™

Catalog No. 89202947 Shop All Abnova Corporation Products
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1 mg x up to 3 Abs
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Catalog No. Quantity
89-202-947 1 mg x up to 3 Abs
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Catalog No. 89-202-947 Supplier Abnova Corporation Supplier No. H00005725K

Item Discontinued This item has been discontinued by the supplier. Please to view product availability in your area.

Description

Includes

Up to three rabbit IgG clones of 1mg each will be delivered to customer.

Rabbit monoclonal antibody raised against a human PTBP1 peptide using ARM Technology.

This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA-binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has four repeats of quasi-RNA recognition motif (RRM) domains that bind RNAs. This protein binds to the intronic polypyrimidine tracts that requires pre-mRNA splicing and acts via the protein degradation ubiquitin-proteasome pathway. It may also promote the binding of U2 snRNP to pre-mRNAs. This protein is localized in the nucleoplasm and it is also detected in the perinucleolar structure. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq

Library Construction: Nonfusion antibody library from rabbit spleen (ARM Technology)
Expression: Overexpression vector and transfection into 293H cell line

Order Info

  1. Customer may provide cell or tissue lysate for antibody screening.
  2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.

Specifications

Antigen PTBP1
Applications ELISA, Western Blot
Classification Monoclonal
Concentration 1mg
Conjugate Unconjugated
Description polypyrimidine tract binding protein 1
Formulation In 1X PBS, pH 7.4
Gene PTBP1
Gene Accession No. PTBP1
Gene Alias HNRNP-I, HNRNPI, HNRPI, MGC10830, MGC8461, PTB, PTB-1, PTB-T, PTB2, PTB3, PTB4, pPTB
Gene Symbols PTBP1
Host Species Rabbit
Immunogen A synthetic peptide of human PTBP1
Quantity 1 mg x up to 3 Abs
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5725
Target Species Human
Content And Storage Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Form Liquid
Isotype IgG
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