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PTK7 Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA520424

Catalog No. PIPA520424


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Description

Description

A suggested positive control is human colon tissue lysate. PA5-20424 can be used with blocking peptide PEP-0541.

Protein-tyrosine kinases (PTKs) play important roles in regulating cell proliferation and differentiation during development. One member of the PTK family, PTK7, has been suggested to regulate the planar cell polarity (PCP) pathway in vertebrates and may play a role in neural convergent extension and neural tube closure. PTK7 has also been implicated in the development of cancer. Loss of PTK7 expression was seen in several melanoma cell lines and biopsies. Conversely, high-throughput analysis of acute myeloid leukemia samples showed an increased level of PTK7 expression compared to normal bone marrow and purified CD34+ cells. Multiple isoforms of PTK7 are known to exist.
Specifications

Specifications

PTK7
Polyclonal
Unconjugated
PTK7
Liquid
PTK7
An 18 amino acid peptide from near the carboxy terminus of human PTK7.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot
1 mg/mL
PBS with 0.02% sodium azide
Q13308, Q8BKG3
CCK4; CCK-4; colon carcinoma kinase 4; colon carcinoma kinase-4; inactive tyrosine-protein kinase 7; protein-tyrosine kinase 7; pseudo tyrosine kinase receptor 7; tyrosine-protein kinase-like 7
Rabbit
IgG
100 μg
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Primary
301242, 5754, 71461
Documents
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