PTK7 Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA520424
A suggested positive control is human colon tissue lysate. PA5-20424 can be used with blocking peptide PEP-0541.Protein-tyrosine kinases (PTKs) play important roles in regulating cell proliferation and differentiation during development. One member of the PTK family, PTK7, has been suggested to regulate the planar cell polarity (PCP) pathway in vertebrates and may play a role in neural convergent extension and neural tube closure. PTK7 has also been implicated in the development of cancer. Loss of PTK7 expression was seen in several melanoma cell lines and biopsies. Conversely, high-throughput analysis of acute myeloid leukemia samples showed an increased level of PTK7 expression compared to normal bone marrow and purified CD34+ cells. Multiple isoforms of PTK7 are known to exist.
|An 18 amino acid peptide from near the carboxy terminus of human PTK7.|
|Antigen affinity chromatography|
|Human, Mouse, Rat|
|Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot|
|PBS with 0.02% sodium azide|
|CCK4; CCK-4; colon carcinoma kinase 4; colon carcinoma kinase-4; inactive tyrosine-protein kinase 7; protein-tyrosine kinase 7; pseudo tyrosine kinase receptor 7; tyrosine-protein kinase-like 7|
|Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C|
|301242, 5754, 71461|
We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.
Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.Ok