PTPRN2 Mouse anti-Human, Clone: 8E12, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA519759
Peptide Sequence: ELADLPKTYL RRPEASSPAR PSKHSVGSER RYSREGGAAL ANALRRHLPF LEALSQAPAS DVLARTHTAQ DRPPAEGDDR FSESILTYVA HTSALTYPPG PRTQLThe protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single intracellular catalytic domain, and thus represents a receptor-type PTP. The catalytic domain of this PTP is most closely related to PTPRN/IA-2beta. This PTP and PTPRN are both found to be major autoantigens associated with insulin-dependent diabetes mellitus. Three alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported.
|PBS with no preservative; pH 7.4|
|IA-2beta, IAR, ICAAR, PTPRP|
|-20° C, Avoid Freeze/Thaw Cycles|
|ELISA, Western Blot|
|PTPRN2 (NP_002838, 108 a.a. ∽ 212 a.a) partial recombit protein with GST tag. MW of the GST tag alone is 26 KDa.|
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