Invitrogen™ PURA Monoclonal Antibody (1D6)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA519766

Catalog No. PIMA519766

Description

Peptide Sequence: TQGQTIALPA QGLIEFRDAL AKLIDDYGVE EEPAELPEGT SLTVDNKRFF FDVGSNKYGV FMRVSEVKPT YRNSITVPYK VWAKFGHTFC KYSEETKKIQ EKQREKRAAC.

This gene product is a sequence-specific, single-stranded DNA-binding protein. It binds preferentially to the single strand of the purine-rich element termed PUR, which is present at origins of replication and in gene flanking regions in a variety of eukaryotes from yeasts through humans. Thus, it is implicated in the control of both DNA replication and transcription. Deletion of this gene has been associated with myelodysplastic syndrome and acute myelogenous leukemia.

Specifications

• Antigen: PURA
• Classification: Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with no preservative; pH 7.4
• Gene Accession No.: Q00577
• Gene Symbols: PURA
• Immunogen: PURA (NP_005850, 183 a.a. ~ 292 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2b κ

• Applications: ELISA, Western Blot, Immunocytochemistry
• Clone: 1D6
• Conjugate: Unconjugated
• Gene: PURA
• Gene Alias: CAGER-1; MRD31; Pur alpha; PUR1; Pura; pura {ECO:0000250; PURALPHA; Pur-alpha; purine rich element binding protein A; purine-rich element binding protein A; purine-rich single-stranded DNA-binding protein alpha; purine-rich single-stranded DNA-binding protein alpha {ECO:0000250; ssCRE-BP; transcriptional activator protein Pur-alpha; transcriptional activator protein Pur-alpha {ECO:0000250; UniProtKB:P42669}
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 5813
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid