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quinolinate phosphoribosyltransferase (A01), Mouse anti-Human, Polyclonal Antibody, Abnova™

Catalog No. 89004565 Shop All Abnova Corporation Products
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89-004-565 50 μL
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Catalog No. 89-004-565 Supplier Abnova Corporation Supplier No. H00023475A01
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Description

Mouse polyclonal antibody raised against a partial recombinant QPRT.

This gene encodes a key enzyme in catabolism of quinolinate, an intermediate in the tryptophan-nicotinamide adenine dinucleotide pathway. Quinolinate acts as a most potent endogenous exitotoxin to neurons. Elevation of quinolinate levels in the brain has been linked to the pathogenesis of neurodegenerative disorders such as epilepsy, Alzheimer's disease, and Huntington's disease. [provided by RefSeq]

Sequence: VEVECSSLQEAVQAAEAGADLVLLDNFKPEELHPTATVLKAQFPSVAVEASGGITLDNLPQFCGPHIDVISMGMLTQAAPALDFSLKLFAKEVAPVPKIH

Specifications

Antigen quinolinate phosphoribosyltransferase
Applications ELISA, Western Blot
Classification Polyclonal
Conjugate Unconjugated
Description Mouse polyclonal antibody raised against a partial recombinant QPRT.
Formulation 50% glycerol
Gene QPRT
Gene Accession No. NM_014298
Gene Alias QPRTase
Gene Symbols QPRT
Host Species Mouse
Immunogen QPRT (NP_055113, 198 a.a. ∼ 297 a.a) partial recombinant protein with GST tag.
Quantity 50 μL
Regulatory Status RUO
Whole Molecule Yes
Primary or Secondary Primary
Gene ID (Entrez) 23475
Target Species Human
Content And Storage Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Form Serum
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