quinolinate phosphoribosyltransferase, Rabbit, Purified MaxPab™ Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against a full-length human QPRT protein.

Manufacturer: Abnova Corporation H00023475D05P

Catalog No. 89-018-100

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    Specifications

    Antigen quinolinate phosphoribosyltransferase
    Applications Western Blotting
    Conjugate Unlabeled
    Cross Reactivity Human
    Description quinolinate phosphoribosyltransferase
    Format Affinity Purified
    Formulation In 1X PBS, pH 7.4
    Gene QPRT
    Gene Accession No. NM_014298.3
    Gene Alias QPRTase
    Gene Symbols QPRT
    Host Species Rabbit
    Immunogen QPRT (NP_055113.2, 1 a.a. ∽297 a.a) full-length human protein.
    Purification Method Protein A column
    Quantity 100μg
    Regulatory Status RUO
    Species Reactivity Human
    Storage Requirements Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
    Primary or Secondary Primary
    Monoclonal or Polyclonal Polyclonal
    Gene ID (Entrez) 23475

    This gene encodes a key enzyme in catabolism of quinolinate, an intermediate in the tryptophan-nicotinamide adenine dinucleotide pathway. Quinolinate acts as a most potent endogenous exitotoxin to neurons. Elevation of quinolinate levels in the brain has been linked to the pathogenesis of neurodegenerative disorders such as epilepsy, Alzheimer's disease, and Huntington's disease. [provided by RefSeq

    Sequence: MDAEGLALLLPPVTLAALVDSWLREDCPGLNYAALVSGAGPSQAALWAKSPGVLAGQPFFDAIFTQLNCQVSWFLPEGSKLVPVARVAEVRGPAHCLLLGERVALNTLARCSGIASAAAAAVEAARGAGWTGHVAGTRKTTPGFRLVEKYGLLVGGAASHRYDLGGLVMVKDNHVVAAGGVEKAVRAARQAADFALKVEVECSSLQEAVQAAEAGADLVLLDNFKPEELHPTATVLKAQFPSVAVEASGGITLDNLPQFCGPHIDVISMGMLTQAAPALDFSLKLFAKEVAPVPKIH

  • Description & Specifications

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