anti-QPRT, MaxPab™ Polyclonal, Abnova

Rabbit Polyclonal

Manufacturer: Abnova Corporation H00023475D05P

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Catalog No. 89-018-100

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    Antigen quinolinate phosphoribosyltransferase
    Conjugate Unlabeled
    Cross Reactivity Human
    Format Affinity Purified
    Host Species Rabbit
    Immunogen QPRT (NP_055113.2, 1 a.a. ∽297 a.a) full-length human protein.
    Purification Method Protein A column
    Quantity 100μg
    Regulatory Status RUO
    Primary or Secondary Primary
    Monoclonal or Polyclonal Polyclonal

    This gene encodes a key enzyme in catabolism of quinolinate, an intermediate in the tryptophan-nicotinamide adenine dinucleotide pathway. Quinolinate acts as a most potent endogenous exitotoxin to neurons. Elevation of quinolinate levels in the brain has been linked to the pathogenesis of neurodegenerative disorders such as epilepsy, Alzheimer's disease, and Huntington's disease.

    Host Species: Rabbit
    Species Reactivity [for Features Main]: Human
    Immunogen: QPRT (NP_055113.2, 1 a.a. ~ 297 a.a) full-length human protein.

    Detection Antibody, Western Blotting

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