Invitrogen™ RAB3A Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA1770

Catalog No. PA1770

Description

PA1-770 detects rab 3A from canine, hamster, human, mouse and rat tissues and cells. PA1-770 has been successfully used in Western blot and immunoprecipitation procedures. By Western blot, this antibody detects an ~21 kDa protein representing rab 3A from Hepa1 cell lysate. PA1-770 immunogen is a synthetic peptide corresponding to residues M(1) A S A T D S R Y G Q K E S S D Q N(18) C of human RAB3A. This sequence is completely conserved between human, mouse, and rat rab 3A. PA1-770 immunizing peptide (Cat. # PEP-098) is available for use in neutralization and control experiments. Recombinant human rab 3A (Cat # RP-770) protein can be purchased for control experiments in Western blot applications.

Rab proteins belong to the Ras small GTPase superfamily. The GTP-binding Rab3 subfamily has 4 known isoforms: 3A, 3B, 3C, and 3D. These proteins are expressed in highest concentrations in brain and endocrine tissues and involved in regulated exocytosis of hormones and neurotransmitters. Specifically, Rab 3s are thought to play a key role in presynaptic vesicle trafficking and priming.

Specifications

• Antigen: RAB3A
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: RAB3A
• Gene Alias: C18A3.6; RAB3; Rab3a; RAB3A, member RAS oncogene family; RAS-associated protein RAB3A; ras-related protein Rab-3A; ras-related protein Rab-3A-like protein; Ras-related small GTP binding protein 3A
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 100759024, 19339, 25531, 484826, 5864
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Immunoprecipitation, Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 1 mg/mL BSA and 0.05% sodium azide
• Gene Accession No.: P20336, P63011, P63012
• Gene Symbols: RAB3A
• Immunogen: Synthetic peptide corresponding to residues M(1) A S A T D S R Y G Q K E S S D Q N(18) C of human RAB3A.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat, Canine, Hamster
• Product Type: Antibody
• Isotype: IgG