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Rabex-5 Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA521117

Catalog No. PIPA521117


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Description

Description

A suggested positive control is rat brain tissue lysate. PA5-21117 can be used with blocking peptide PEP-1231.

RABEX5 is a guanine nucleotide exchange factor (GEF) that forms a complex with rabaptin-5 and specifically activates Rab5, a small GTPase that plays an essential role in endocytic traffic. RABEX-5 is thought to also interact with another member of the Rab family, Rab22, which targets RABEX5 to early endosomes, allowing it to activate Rab5 and thereby promote Rab5-mediated endosome fusion.
Specifications

Specifications

Rabex-5
Polyclonal
Unconjugated
RABGEF1
Liquid
RABGEF1
A 19 amino acid peptide near the center terminus of human RABEX5.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot
1 mg/mL
PBS with 0.02% sodium azide
Q9UJ41, Q9JM13
RABEX5, rabex-5; RAP1; rab5 GDP/GTP exchange factor; rabaptin-5-associated exchange factor for Rab5
Rabbit
IgG
100 μg
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Primary
27342, 360797, 56715
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