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RAD18 homolog (S. cerevisiae), Mouse, Clone: 3H7, Abnova™

Catalog No. 89014321 Shop All Abnova Corporation Products
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89-014-321 100 μg
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Catalog No. 89-014-321 Supplier Abnova Corporation Supplier No. H00056852M01
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Description

Mouse monoclonal antibody raised against a partial recombinant RAD18.

The protein encoded by this gene is highly similar to S. cerevisiae DNA damage repair protein Rad18. Yeast Rad18 functions through its interaction with Rad6, which is an ubiquitin-conjugating enzyme required for post-replication repair of damaged DNA. Similar to its yeast counterpart, this protein is able to interact with the human homolog of yeast Rad6 protein through a conserved ring-finger motif. Mutation of this motif results in defective replication of UV-damaged DNA and hypersensitivity to multiple mutagens. [provided by RefSeq

Sequence: EKEIDEIHSKYRKKHKSEFQLLVDQARKGYKKIAGMSQKTVTITKEDESTEKLSSVCMGQEDNMTSVTNHFSQSKLDSPEELEPDREEDSSSCIDIQEV

Specifications

Antigen RAD18 homolog (S. cerevisiae)
Applications ELISA, Immunofluorescence, Immunohistochemistry (PFA fixed), KnockDown, Western Blot
Classification Monoclonal
Clone 3H7
Conjugate Unconjugated
Description Mouse monoclonal antibody raised against a partial recombinant RAD18.
Formulation PBS with no preservative; pH 7.4
Gene RAD18
Gene Accession No. NM_020165
Gene Alias RNF73
Gene Symbols RAD18
Host Species Mouse
Immunogen RAD18 (NP_064550, 332 a.a. ∼ 430 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification Method Affinity Purified
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 56852
Target Species Human, Rat
Content And Storage Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Product Type Antibody
Isotype IgG2b κ
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