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RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae), Mouse, Purified MaxPab™ Polyclonal Antibody, Abnova™ Available on GSA/VA Contract for Federal Government customers only.

Mouse polyclonal antibody raised against a full-length human RAD51 protein.

Manufacturer:  Abnova Corporation H00005888B01P

Catalog No. 89-018-889


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Specifications

Description

The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51, and are known to be involved in the homologous recombination and repair of DNA. This protein can interact with the ssDNA-binding protein RPA and RAD52, and it is thought to play roles in homologous pairing and strand transfer of DNA. This protein is also found to interact with BRCA1 and BRCA2, which may be important for the cellular response to DNA damage. BRCA2 is shown to regulate both the intracellular localization and DNA-binding ability of this protein. Loss of these controls following BRCA2 inactivation may be a key event leading to genomic instability and tumorigenesis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq

Sequence: MAMQMQLEANADTSVEEESFGPQPISRLEQCGINANDVKKLEEAGFHTVEAVAYAPKKELINIKGISEAKADKILAEAAKLVPMGFTTATEFHQRRSEIIQITTGSKELDKLLQGGIETGSITEMFGEFRTGKTQICHTLAVTCQLPIDRGGGEGKAMYIDTEGTFRPERLLAVAERYGLSGSDVLDNVAYARAFNTDHQTQLLYQASAMMVESRYALLIVDSATALYRTDYSGRGELSARQMHLARFLRMLLRLADEFGVAVVITNQVVAQVDGAAMFAADPKKPIGGNIIAHASTTRLYLRKGRGETRICKIYDSPCLPEAEAMFAINADGVGDAKD
Description & Specifications

Specifications

RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae)
Unlabeled
RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae)
In 1X PBS, pH 7.4
NM_002875
RAD51
RAD51 (NP_002866.2, 1 a.a. ∽339 a.a) full-length human protein.
50μg
Human, Mouse, Rat
Primary
5888
Immunofluorescence,Immunohistochemistry (Paraffin),Western Blot
Human,Mouse,Rat
Affinity Purified
RAD51
BRCC5, HRAD51, HsRad51, HsT16930, RAD51A, RECA
Murine
Protein A column
RUO
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Polyclonal
Human,Murine,Rat
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