anti-RAD51, MaxPab™ Polyclonal, Abnova Available on GSA/VA Contract for Federal Government customers only.

Mouse Polyclonal

Manufacturer: Abnova Corporation H00005888B01P

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Catalog No. 89-018-889

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    Antigen RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae)
    Conjugate Unlabeled
    Cross Reactivity Human,Mouse,Rat
    Format Affinity Purified
    Host Species Mouse
    Immunogen RAD51 (NP_002866.2, 1 a.a. ∽339 a.a) full-length human protein.
    Purification Method Protein A column
    Quantity 50μg
    Regulatory Status RUO
    Primary or Secondary Primary
    Monoclonal or Polyclonal Polyclonal

    The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51, and are known to be involved in the homologous recombination and repair of DNA. This protein can interact with the ssDNA-binding protein RPA and RAD52, and it is thought to play roles in homologous pairing and strand transfer of DNA. This protein is also found to interact with BRCA1 and BRCA2, which may be important for the cellular response to DNA damage. BRCA2 is shown to regulate both the intracellular localization and DNA-binding ability of this protein. Loss of these controls following BRCA2 inactivation may be a key event leading to genomic instability and tumorigenesis. Multiple transcript variants encoding different isoforms have been found for this gene.

    Host Species: Mouse
    Species Reactivity [for Features Main]: Human, Mouse, Rat
    Immunogen: RAD51 (NP_002866.2, 1aa ~ 339aa) full-length human protein

    Detection Antibody, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blotting

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