RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae), Rabbit, Purified MaxPab™ Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against a full-length human RAD51 protein.

Manufacturer: Abnova Corporation H00005888D01P

Catalog No. 89-018-415

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    Specifications

    Antigen RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae)
    Applications Immunofluorescence,Immunohistochemistry (Paraffin),Western Blotting
    Conjugate Unlabeled
    Cross Reactivity Human
    Description RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae)
    Format Affinity Purified
    Formulation In 1X PBS, pH 7.4
    Gene RAD51
    Gene Accession No. NM_002875
    Gene Alias BRCC5, HRAD51, HsRad51, HsT16930, RAD51A, RECA
    Gene Symbols RAD51
    Host Species Rabbit
    Immunogen RAD51 (NP_002866.2, 1 a.a. ∽339 a.a) full-length human protein.
    Purification Method Protein A column
    Quantity 100μg
    Regulatory Status RUO
    Species Reactivity Human
    Storage Requirements Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
    Primary or Secondary Primary
    Monoclonal or Polyclonal Polyclonal
    Gene ID (Entrez) 5888

    The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51, and are known to be involved in the homologous recombination and repair of DNA. This protein can interact with the ssDNA-binding protein RPA and RAD52, and it is thought to play roles in homologous pairing and strand transfer of DNA. This protein is also found to interact with BRCA1 and BRCA2, which may be important for the cellular response to DNA damage. BRCA2 is shown to regulate both the intracellular localization and DNA-binding ability of this protein. Loss of these controls following BRCA2 inactivation may be a key event leading to genomic instability and tumorigenesis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq

    Sequence: MAMQMQLEANADTSVEEESFGPQPISRLEQCGINANDVKKLEEAGFHTVEAVAYAPKKELINIKGISEAKADKILAEAAKLVPMGFTTATEFHQRRSEIIQITTGSKELDKLLQGGIETGSITEMFGEFRTGKTQICHTLAVTCQLPIDRGGGEGKAMYIDTEGTFRPERLLAVAERYGLSGSDVLDNVAYARAFNTDHQTQLLYQASAMMVESRYALLIVDSATALYRTDYSGRGELSARQMHLARFLRMLLRLADEFGVAVVITNQVVAQVDGAAMFAADPKKPIGGNIIAHASTTRLYLRKGRGETRICKIYDSPCLPEAEAMFAINADGVGDAKD

  • Description & Specifications

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