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RASGRP1, Rabbit, Monoclonal Antibody, Abnova™

Catalog No. 89201498 Shop All Abnova Corporation Products
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1 mg x up to 3 Abs
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Catalog No. Quantity
89-201-498 1 mg x up to 3 Abs
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Catalog No. 89-201-498 Supplier Abnova Corporation Supplier No. H00010125K

Description

Includes

Up to three rabbit IgG clones of 1mg each will be delivered to customer.

Rabbit monoclonal antibody raised against a human RASGRP1 peptide using ARM Technology.

This gene is a member of a family of genes characterized by the presence of a Ras superfamily guanine nucleotide exchange factor (GEF) domain. It functions as a diacylglycerol (DAG)-regulated nucleotide exchange factor specifically activating Ras through the exchange of bound GDP for GTP. It activates the Erk/MAP kinase cascade and regulates T-cells and B-cells development, homeostasis and differentiation. Alternatively spliced transcript variants encoding different isoforms have been identified. Altered expression of the different isoforms of this protein may be a cause of susceptibility to systemic lupus erythematosus (SLE). [provided by RefSeq

Library Construction: Nonfusion antibody library from rabbit spleen (ARM Technology)
Expression: Overexpression vector and transfection into 293H cell line

Order Info

  1. Customer may provide cell or tissue lysate for antibody screening.
  2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.

Specifications

Antigen RASGRP1
Applications ELISA, Western Blot
Classification Monoclonal
Concentration 1mg
Conjugate Unconjugated
Description RAS guanyl releasing protein 1 (calcium and DAG-regulated)
Formulation In 1X PBS, pH 7.4
Gene RASGRP1
Gene Accession No. RASGRP1
Gene Alias CALDAG-GEFI, CALDAG-GEFII, MGC129998, MGC129999, RASGRP, V, hRasGRP1
Gene Symbols RASGRP1
Host Species Rabbit
Immunogen A synthetic peptide of human RASGRP1
Quantity 1 mg x up to 3 Abs
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10125
Target Species Human
Content And Storage Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Form Liquid
Isotype IgG
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