RAS guanyl releasing protein 3 (calcium and DAG-regulated), Mouse, Polyclonal Antibody, Abnova
Mouse polyclonal antibody raised against a partial recombinant RASGRP3.
Manufacturer: Abnova Corporation H00025780A01
Members of the RAS (see HRAS; MIM 190020) subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RASGRP3, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation (Rebhun et al., 2000 [PubMed 10934204]).[supplied by OMIMSequence: AGHRDLDSRAITLVTGSSRKISVRLQRATTSQATQTEPVWSEAGWGDSGSHTFPKMKSKFHDKAAKDKGFAKWENEKPRVHAGVDVVDRGTEFELDQDEGEETRQDGEDG
|RAS guanyl releasing protein 3 (calcium and DAG-regulated)|
|Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|ELISA, Western Blot|
|Mouse polyclonal antibody raised against a partial recombinant RASGRP3.|
|RASGRP3 (AAH27849, 581 a.a. ~ 690 a.a) partial recombinant protein with GST tag.|
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