Invitrogen™ RASSF10 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA521151

Catalog No. PIPA521151

Description

A suggested positive control is human lung tissue lysate. PA5-21151 can be used with blocking peptide PEP-1265.

RASSF10 is a member of the N-terminal Ras association domain-containing family of proteins, a family of tumor suppressor genes that are frequently epigenetically inactivated in cancer. These proteins consist of RASSF7-10 and are structurally distinct from RASSF1-6, containing the N-terminal Ras association domain but lacking the Sav/RASSF/Hippo protein interaction domains. While little is known of the function of RASSF10, it is inactivated in both childhood leukemia and gliomas. In secondary glioblastomas, RASSF10 methylation can be used as an independent prognostic associated with worst progression-free survival and overall survival.

Specifications

• Antigen: RASSF10
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: RASSF10
• Gene Alias: 4632411J06Rik; Ras association (RalGDS/AF-6) domain family (N-terminal) member 10; Ras association domain family member 10; ras association domain-containing protein 10; Rassf10
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 644943
• Content And Storage: 4°C
• Form: Liquid

• Applications: Immunohistochemistry, Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% sodium azide
• Gene Accession No.: A6NK89
• Gene Symbols: RASSF10
• Immunogen: A 17 amino acid peptide near the amino terminus of human RASSF10.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov