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RASSF10 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA521151

Catalog No. PIPA521151


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Description

Description

A suggested positive control is human lung tissue lysate. PA5-21151 can be used with blocking peptide PEP-1265.

RASSF10 is a member of the N-terminal Ras association domain-containing family of proteins, a family of tumor suppressor genes that are frequently epigenetically inactivated in cancer. These proteins consist of RASSF7-10 and are structurally distinct from RASSF1-6, containing the N-terminal Ras association domain but lacking the Sav/RASSF/Hippo protein interaction domains. While little is known of the function of RASSF10, it is inactivated in both childhood leukemia and gliomas. In secondary glioblastomas, RASSF10 methylation can be used as an independent prognostic associated with worst progression-free survival and overall survival.
Specifications

Specifications

RASSF10
Polyclonal
Unconjugated
RASSF10
Liquid
RASSF10
A 17 amino acid peptide near the amino terminus of human RASSF10.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Immunohistochemistry, Western Blot
1 mg/mL
PBS with 0.02% sodium azide
A6NK89
ras association domain-containing protein 10
Rabbit
IgG
100 μg
4° C
Primary
644943
Documents
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