MilliporeSigma™ anti-RBPMS, Polyclonal

Rabbit Polyclonal Antibody

Supplier:  MilliporeSigma™ ABN1362

Catalog No. ABN1362MI

Description

Specifically detects RBPMS Clone: in Human, Mouse, Rat samples, and it is validated for Immunofluorescence, Western Blotting

RNA-binding protein with multiple splicing (UniProt Q93062; also known as Heart and RRM expressed sequence, Hermes, RBP-MS) is encoded by the RBPMS (also known as HERMES) gene (Gene ID 11030) in human. RBPMS is a member of the RRM (RNA recognition motif) family of RNA-binding proteins. Transcriptome-wide study using photoactivatable-ribonucleoside-enhanced crosslinking and immunoprecipitation (PAR-CLIP) in HEK293 cells reveals both exonic mature and intronic pre-mRNA-binding sites, in agreement with the nuclear and cytoplasmic localization of the RRM family proteins. RBPMS is found to be exclusively expressed in retinal ganglion cells (RGCs) and displaced RGCs (dRGCs). RBPMS expression can therefore be utitized as a RGC marker, and the RBPMS gene promoter could be utilized for driving RGC-specific transgene expression.

Specifications

• Antigen: RBPMS
• Classification: Polyclonal
• Formulation: Purified rabbit polyclonal antibody in PBS with 1% BSA and 0.09 % sodium azide.
• Gene Symbols: RBPMS, HERMES
• Immunogen: KLH-conjugated linear peptide corresponding to a sequence from the N-terminal region of human RBPMS.
• Quantity: 100 μg
• Research Discipline: Neuroscience
• Gene ID (Entrez): NP_001008710
• Target Species: Human, Mouse, Rat

• Applications: Immunofluorescence, Western Blot
• Conjugate: Unconjugated
• Gene Accession No.: Q93062
• Host Species: Rabbit
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Test Specificity: Expected to react with all five spliced isoforms (UniProt Q93062-1 through Q93062-5).
• Content And Storage: 2°C to 8°C for one year

For Research Use Only