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MilliporeSigma™ anti-Relaxin 2, Polyclonal

Rabbit Polyclonal Antibody

Manufacturer:  MilliporeSigma™ 553850100UG

Catalog No. 55-385-0100UG


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Description

Description

Specifically detects Relaxin 2 Clone: in Human samples, and it is validated for ELISA, Immunohistochemistry, Radioimmunoassay

Relaxin is a hormone of the insulin-growth factor family that induces ripening of the cervix prior to childbirth. The peptide is composed of two chains, A and B, and is formed from a single-chain prohormone, similar to insulin. Relaxin has also been shown to elicit a powerful vasodilatory response in several target organs. This response is mediated by the stimulation of intrinsic nitric oxide (NO) generation. Additionally, relaxin plays a role in extracellular matrix (ECM) remodeling in many reproductive organs, including the ovary, by upregulating MMP-1, MMP-3, and MMP-9 activity. In the human there are two relaxin genes, H1 and H2, which share 90% sequence homology within their coding region.
Specifications

Specifications

Relaxin 2
Unconjugated
purified
human relaxin-2
100μg
2°C to 8°C
Polyclonal
Human
ELISA, Immunohistochemistry, Radioimmunoassay
Lyophilized from 50mM Tris, pH 7.5.
Rabbit
IgG
RUO
Primary
Recognizes the relaxin-2 protein.
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