MilliporeSigma™ anti-Relaxin 2, Polyclonal

Rabbit Polyclonal Antibody

Manufacturer:  MilliporeSigma™ 553850100UG

Catalog No. 55-385-0100UG

Description

Specifically detects Relaxin 2 Clone: in Human samples, and it is validated for ELISA, Immunohistochemistry, Radioimmunoassay

Relaxin is a hormone of the insulin-growth factor family that induces ripening of the cervix prior to childbirth. The peptide is composed of two chains, A and B, and is formed from a single-chain prohormone, similar to insulin. Relaxin has also been shown to elicit a powerful vasodilatory response in several target organs. This response is mediated by the stimulation of intrinsic nitric oxide (NO) generation. Additionally, relaxin plays a role in extracellular matrix (ECM) remodeling in many reproductive organs, including the ovary, by upregulating MMP-1, MMP-3, and MMP-9 activity. In the human there are two relaxin genes, H1 and H2, which share 90% sequence homology within their coding region.

Specifications

• Antigen: Relaxin 2
• Conjugate: Unconjugated
• Format: purified
• Immunogen: human relaxin-2
• Quantity: 100μg
• Storage Requirements: 2°C to 8°C
• Monoclonal or Polyclonal: Polyclonal
• Target Species: Human

• Applications: ELISA, Immunohistochemistry, Radioimmunoassay
• Formulation: Lyophilized from 50mM Tris, pH 7.5.
• Host Species: Rabbit
• Isotype: IgG
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Test Specificity: Recognizes the relaxin-2 protein.

For Research Use Only