anti-Retinoic Acid Receptor, Beta (hRARBeta) Ab-2, Clone: 336, same as H1/H12, Epredia™ LabVision

Catalog No.	Quantity	Concentration
MS1342P	1 mL	200μg/mL
MS1342P1	500 μL	200μg/mL
MS1342P1ABX	100 μL	1mg/mL
MS1342PABX	200 μL	1mg/mL
MS1342R7	7 mL	—
MS1342PCS	5 Slides	—

Catalog No. MS1342P Supplier Epredia Supplier No. MS1342P

Description

Mouse Monoclonal Antibody

Retinoids are metabolites of vitamin A (retinal) and are believed to represent important signaling molecules during vertebrate development and tissue differentiation. Two families of retinoid receptors have been identified. Retinoic acid receptors (RARs) include RARα, RARΒ and RARγ, each of which has a high affinity for all-trans retinoic acids and belongs to the same class of nuclear transcription factors as thyroid hormone receptors, vitamin D3 receptor and ecdysone receptor. The ligand binding domains of the RARs are highly conserved and RAR isoforms are expressed in distinct patterns throught development and in the mature organism. Members of the retinoid X receptor (RXR) family, RXRα, RXRΒ and RXRγ, are activated by 9-cis-retinoic acid, a stereo- and photoisomer of all-trans-RA that is expressed in vivo in both liver and kidney and may represent a widely used hormone.

Host Species: Mouse
Clone: 336; same as H1/H12
Isotype: IgG1/κ
Cross Reactivity: Human. Others-not known.
Epitope: aa 11-25
Immunogen: Synthetic peptide corresponding to aa 11-25 (SPGQILDFYTASPSS) from N-terminus of human RARΒ.
Molecular Weight: 54kDa
Positive Control: HeLa cells. Colon CA.
Cellular Localization: Nuclear

Immunohistochemistry (Formalin/Paraffin)

Abbreviations: AP=Affinity Purification, ChIP=Chromatin IP, CM=Confocal Microscopy, DB=Dot Blot, EIA=ELISA, EM=Electron Microscopy, FC=Flow Cytometry, GS=Gel Supershift, IC=Immunocytochemistry, IF=Immunofluorescence, IH=Immunohistology/Immunohistochemistry, IP=Immunoprecipitation, IPK=IP Kinase Assay, KA=Kinase Assay, NEUT=Neutralization, PIA=Peptide Inhibition Assay, RIA=Radioimmunossay, TCA=T Cell Activation, WB=Western Blotting, Species: Am=Amphibian, Av=Avian, B=Bovine, Ca=Cat ,Ck=Chicken, D=Dog, Dr=Deer, Ds=Drosophila, El=Elk, Fg=Frog, Fs=Fish, Ft=Ferret, G=Goat, Gp=Guinea Pig, H=Horse, Hm=Hamster, Hu=Human, K=Kangaroo, Ms=Mouse, Nhp=Non-Human Primate, O=Ovine, P=Porcine, Rb=Rabbit, Rp=Reptile, Rt=Rat, Ys=Yeast, Xn=Xenopus, (wk)=cross reacts weakly

Specifications

• Antigen: Retinoic Acid Receptor Β (hRARΒ) Ab-2
• Classification: Monoclonal
• Concentration: 200μg/mL
• Conjugate: Unconjugated
• Host Species: Mouse
• Immunogen: Synthetic peptide corresponding to aa 11-25 (SPGQILDFYTASPSS) from N-terminus of human RARBeta.
• Purification Method: HeLa cells, colon CA
• Quantity: 1 mL
• Primary or Secondary: Primary
• Target Species: Human
• Content And Storage: 2–8 degrees
• Form: Purified
• Isotype: IgG1 κ