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Description
Includes
Up to three rabbit IgG clones of 1mg each will be delivered to customer.
Major histocompatibility (MHC) class II molecules are transmembrane proteins that have a central role in development and control of the immune system. The protein encoded by this gene, along with regulatory factor X-associated protein and regulatory factor-5, forms a complex that binds to the X box motif of certain MHC class II gene promoters and activates their transcription. Once bound to the promoter, this complex associates with the non-DNA-binding factor MHC class II transactivator, which controls the cell type specificity and inducibility of MHC class II gene expression. This protein contains ankyrin repeats involved in protein-protein interactions. Mutations in this gene have been linked to bare lymphocyte syndrome type II, complementation group B. Two transcript variants encoding different isoforms have been described for this gene, with only one isoform showing activation activity. [provided by RefSeq
Expression: Overexpression vector and transfection into 293H cell line
Order Info
- Customer may provide cell or tissue lysate for antibody screening.
- Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
Specifications
Specifications
| Antigen | RFXANK |
| Applications | ELISA, Western Blot |
| Classification | Monoclonal |
| Concentration | 1mg |
| Conjugate | Unconjugated |
| Description | regulatory factor X-associated ankyrin-containing protein |
| Formulation | In 1X PBS, pH 7.4 |
| Gene | RFXANK |
| Gene Accession No. | RFXANK |
| Gene Alias | ANKRA1, BLS, F14150_1, MGC138628, RFX-B |
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