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RGR, Rabbit, Monoclonal Antibody, Abnova™
Rabbit monoclonal antibody raised against a human RGR peptide using ARM Technology.
Supplier: Abnova Corporation H00005995K
Includes: Up to three rabbit IgG clones of 1mg each will be delivered to customer.
Description
This gene encodes a putative retinal G-protein coupled receptor. The gene is a member of the opsin subfamily of the 7 transmembrane, G-protein coupled receptor 1 family. Like other opsins which bind retinaldehyde, it contains a conserved lysine residue in the seventh transmembrane domain. The protein acts as a photoisomerase to catalyze the conversion of all-trans-retinal to 11-cis-retinal. The reverse isomerization occurs with rhodopsin in retinal photoreceptor cells. The protein is exclusively expressed in tissue adjacent to retinal photoreceptor cells, the retinal pigment epithelium and Mueller cells. This gene may be associated with autosomal recessive and autosomal dominant retinitis pigmentosa (arRP and adRP, respectively). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq
Library Construction: Nonfusion antibody library from rabbit spleen (ARM Technology)Expression: Overexpression vector and transfection into 293H cell line
Order Info
- Customer may provide cell or tissue lysate for antibody screening.
- Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
Specifications
RGR | |
Monoclonal | |
Unconjugated | |
In 1X PBS, pH 7.4 | |
RGR | |
Rabbit | |
1 mg x up to 3 Abs | |
Primary | |
Human | |
Liquid |
ELISA, Western Blot | |
1mg | |
retinal G protein coupled receptor | |
RGR | |
RGR | |
A synthetic peptide of human RGR | |
RUO | |
5995 | |
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. | |
IgG |
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