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RHOC, Mouse, Clone: 1B7, Abnova™

Mouse monoclonal antibody raised against a full-length recombinant RHOC.

Supplier:  Abnova Corporation H00000389M06

Catalog No. 89-016-204


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Description

Description

This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The protein encoded by this gene is prenylated at its C-terminus, and localizes to the cytoplasm and plasma membrane. It is thought to be important in cell locomotion. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq

Sequence: MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYIADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRQDEHTRRELAKMKQEPVRSEEGRDMANRISAFGYLECSAKTKEGVREVFEMATRAGLQVRKNKRRRGCPIL
Specifications

Specifications

RHOC
Monoclonal
Unconjugated
PBS with no preservative; pH 7.4
BC007245
RHOC
RHOC (AAH07245, 1 a.a. ∼ 193 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
100 μg
Primary
Human, Mouse, Rat
Antibody
IgG2a κ
ELISA, Immunofluorescence, Western Blot
1B7
Mouse monoclonal antibody raised against a full-length recombinant RHOC.
RHOC
ARH9/ARHC/H9/MGC1448/MGC61427/RHOH9
Mouse
Affinity chromatography
RUO
389
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Liquid
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