RHOC, Mouse, Clone: 1B7, Abnova™

Catalog No.	Quantity
89-016-204	100 μg

Catalog No. 89-016-204 Supplier Abnova Corporation Supplier No. H00000389M06

Description

Mouse monoclonal antibody raised against a full-length recombinant RHOC.

This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The protein encoded by this gene is prenylated at its C-terminus, and localizes to the cytoplasm and plasma membrane. It is thought to be important in cell locomotion. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq

Sequence: MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYIADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRQDEHTRRELAKMKQEPVRSEEGRDMANRISAFGYLECSAKTKEGVREVFEMATRAGLQVRKNKRRRGCPIL

Specifications

• Antigen: RHOC
• Applications: ELISA, Immunofluorescence, Western Blot
• Classification: Monoclonal
• Clone: 1B7
• Conjugate: Unconjugated
• Description: Mouse monoclonal antibody raised against a full-length recombinant RHOC.
• Formulation: PBS with no preservative; pH 7.4
• Gene: RHOC
• Gene Accession No.: BC007245
• Gene Alias: ARH9/ARHC/H9/MGC1448/MGC61427/RHOH9
• Gene Symbols: RHOC
• Host Species: Mouse
• Immunogen: RHOC (AAH07245, 1 a.a. ∼ 193 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
• Purification Method: Affinity chromatography
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 389
• Target Species: Human, Mouse, Rat
• Content And Storage: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG2a κ