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RORγt Mouse anti-Mouse, Brilliant Violet 786, Clone: Q31-378, BD

Catalog No. BDB564723 Shop All BD Biosciences Products
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BDB564723 50 μg
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Catalog No. BDB564723 Supplier BD Biosciences Supplier No. 564723
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Description

Mouse Monoclonal Antibody

The Q31-378 monoclonal antibody recognizes mouse RORgamma t (RORγt) , an isoform of RORgamma (RORγ). RORγt is a DNA-binding transcription factor that belongs to the ROR/RZR orphan nuclear receptor family. RORγt is expressed exclusively by lymphoid cells including CD4+CD8+ thymocytes, peripheral CD4+ Th17 and CD8+ Tc17 cells, NKT cells and innate lymphoid cells such as lymphoid tissue inducer (LT i) cells. RORγt plays essential roles in thymopoiesis, T cell homeostasis, differentiation of effector T lymphocytes and the development of secondary lymphoid tissues including lymph nodes and Peyer’s patches.

The antibody was conjugated to BD Horizon BV786 which is part of the BD Horizon Brilliant™ Violet family of dyes. This dye is a tandem fluorochrome of BD Horizon BV421 with an Ex Max of 405-nm and an acceptor dye with an Em Max at 786-nm. BD Horizon BV786 can be excited by the violet laser and detected in a filter used to detect Cy™7-like dyes (eg, 780/60-nm filter).

TRUSTED_SUSTAINABILITY

Specifications

Antigen RORγt
Applications Flow Cytometry
Classification Monoclonal
Clone Q31-378
Concentration 0.2mg/mL
Conjugate Brilliant Violet 786
Description RORγT; RORgt; RORgamma t; RORgammaT; Rorc2; Rorg; TOR; Thor; Nr1f3
Formulation Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Host Species Mouse
Immunogen Mouse RORγt Recombinant Protein
Purification Method Affinity Purified
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Mouse
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG2a κ
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