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Description
The Q31-378 monoclonal antibody recognizes RORgamma t (RORγt), an isoform of RORgamma (RORγ). RORγt is a DNA-binding transcription factor that belongs to the ROR/RZR orphan nuclear receptor family. RORγt is expressed exclusively by lymphoid cells including CD4+CD8+ thymocytes, peripheral CD4+ Th17 and CD8+ Tc17 cells, NKT cells and innate lymphoid cells such as lymphoid tissue inducer (LTi) cells. RORγt plays essential roles in thymopoiesis, T cell homeostasis, differentiation of effector T lymphocytes and the development of secondary lymphoid tissues including lymph nodes and Peyer's patches.
Host Species: Mouse
Clone: Q31-378
Isotype: IgG2a, κ
Species Reactivity: Mouse
Immunogen: Mouse RORγt Recombinant Protein
Intracellular Staining
Specifications
Specifications
| Antigen | RORγt |
| Applications | Flow Cytometry |
| Classification | Monoclonal |
| Clone | Q31-378 |
| Concentration | 0.2mg/mL |
| Conjugate | PE |
| Description | RORγT; RORgt; RORgamma t; RORgammaT; Rorc2; Rorg; TOR; Thor; Nr1f3 |
| Formulation | Aqueous buffered solution containing ≤0.09% sodium azide. |
| Host Species | Mouse |
| Immunogen | Mouse RORγt Recombinant Protein |
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Safety and Handling
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