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RORgt Mouse, Unlabeled, Clone: O28-835, BD

Catalog No. BDB562197 Shop All BD Biosciences Products
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BDB562197 0.1 mg
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Catalog No. BDB562197 Supplier BD Biosciences Supplier No. 562197
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Description

Mouse Monoclonal Antibody

The O28-835 monoclonal antibody recognizes ROR-gamma ( RORγ) and its isoform, RORγt. RORγ(∽58 kDa calculated molecular weight) is a DNA-binding transcription factor that belongs to the ROR/RZR orphan nuclear receptor family. It is expressed in different tissues including skeletal muscle, kidney, liver and adipose tissues. RORγt ( ∽56 kDa calculated molecular weight ) is a RORγisoform that is expressed exclusively by lymphoid cells. It is expressed by various lymphoid cell types including CD4+CD8+ thymocytes, peripheral CD4+ Th17 and CD8+ Tc17 cells and lymphoid tissue inducer (Lti) cells. RORγt plays essential roles in thymopoiesis, T cell homeostasis, differentiation of effector T lymphocytes and the development of secondary lymphoid tissues including lymph nodes and Peyer’s patches.

TRUSTED_SUSTAINABILITY

Specifications

Antigen RORgt
Applications Western Blot
Classification Monoclonal
Clone O28-835
Concentration 0.5mg/mL
Conjugate Unconjugated
Description Rorc; Rorg; RORgamma; Rorγ; RORgt; RORgammat; RORγt; TOR; Thor; Nr1f3; ROR
Formulation Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species Mouse
Immunogen Human RORγt Recombinant Protein
Purification Method Affinity Purified
Quantity 0.1 mg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Human, Mouse
Content And Storage Store undiluted at 4°C
Isotype IgG2b κ
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