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RORgt Mouse, Unlabeled, Clone: O28-835, BD

Mouse Monoclonal Antibody

Supplier:  BD Biosciences 562197

Catalog No. BDB562197


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Description

Description

The O28-835 monoclonal antibody recognizes ROR-gamma ( RORγ) and its isoform, RORγt. RORγ(∽58 kDa calculated molecular weight) is a DNA-binding transcription factor that belongs to the ROR/RZR orphan nuclear receptor family. It is expressed in different tissues including skeletal muscle, kidney, liver and adipose tissues. RORγt ( ∽56 kDa calculated molecular weight ) is a RORγisoform that is expressed exclusively by lymphoid cells. It is expressed by various lymphoid cell types including CD4+CD8+ thymocytes, peripheral CD4+ Th17 and CD8+ Tc17 cells and lymphoid tissue inducer (Lti) cells. RORγt plays essential roles in thymopoiesis, T cell homeostasis, differentiation of effector T lymphocytes and the development of secondary lymphoid tissues including lymph nodes and Peyer’s patches.

TRUSTED_SUSTAINABILITY
Specifications

Specifications

RORgt
Monoclonal
0.5mg/mL
Rorc; Rorg; RORgamma; Rorγ; RORgt; RORgammat; RORγt; TOR; Thor; Nr1f3; ROR
Mouse
Affinity Purified
RUO
Human, Mouse
IgG2b κ
Western Blot
O28-835
Unconjugated
Aqueous buffered solution containing ≤0.09% sodium azide.
Human RORγt Recombinant Protein
0.1 mg
Primary
Store undiluted at 4°C
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